Economic growth is a long-term increase in the capability of a region for providing more types of economic goods to the population. The aim of this study was to analyze the factors that influence economic growth in Province of Special Religion Yogyakarta in 2014-2018. This research used four independent variables, there are total of labour, education level, torism rate, and goverment spending. The data used in this research is secondary data analysis method used in this research is the analysis of panel data regression. Results obtained from time series panel data regression analysis that Pooled Least Square (PLS),while for cross section panel data result if Fixed Effect Method (FEM) more appropriate to use than PLS and REM. Based on test validity or the effect of the t test, that the variables that significantly influence of economic growth in province of Special Religion Yogyakarta in 2014-2018 is only Education Level variable with a positive influence.