The patient care manager has a central role in addressing gaps between providers, care teams, settings, and information in care planning and patient flow. In other words, MPP must act as a change agent in health care. Changes in health care organizations are required to provide a service model that promotes cost control and coordination of care, including responsible care organizations. Case Manager required to understand how its role and contribution in changing health care organizations. This study explores the concept of organizational change and the role of change agents to help case manager in developing managerial skills to change health services. This is library research with data taken from books and journal articles related to Organizational Change Theory and Change Management. The data was collected through documentation using a research material classification checklist, writing scheme/map, and research record format. Data then analyzed using content analysis methods. Case management encourages client involvement and direct communication between the service manager, the client, the client's family or family caregiver, and staff, to optimize health outcomes for all concerned. The case manager as a change agent has an important role in explaining change efforts, as well as monitoring resistance in order to modify change to suit the preferences of organizational members. The case manager is required to have clinical, managerial, and financial skills, and play a key role in ensuring quality as a series of aspects of efficiency, effectiveness, safety, suitability, participation, and equality. The implementation of case management in Indonesia still faces various challenges and also faced with an ethical dilemma of the roles he plays. The case manager also often experiences difficulties in balancing the demands of the patient advocacy role and the role of gatekeeper for the institution he works for.